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. 2019 Oct 23;10:1267. doi: 10.3389/fphar.2019.01267

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Copyright © 2019 Qiu, Cao, Wang, Zhang, Wei, Hao, Mu and Lin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Echocardiographic assessment after 28 days and 60 days of drug administration. Sham, sham group; Model, model group; Fosinopril, fosinopril group; BXYS (0.4g/kg), Buxin Yishen 0.4g/kg treated group; BXYS (0.8g/kg), Buxin Yishen 0.8g/kg treated group. **P < 0.01 vs. sham group. ^#P < 0.05, ^##P < 0.01 vs. model group. ⁺P < 0.05, ⁺⁺ P < 0.01 vs. fosinopril group. (A) Left ventricular internal diameter at end-diastolic (LVIDd) after 28 days. (B) Left ventricular internal diameter at end-systolic (LVIDs) after 28 days. (C) Ejection fraction (EF) after 28 days. (D) Fractional shortening (FS) after 28 days. (E–H) LVIDd, LVIDs, EF, FS after 60 days of drug administration.