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. 2019 Oct 23;10:1267. doi: 10.3389/fphar.2019.01267

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Copyright © 2019 Qiu, Cao, Wang, Zhang, Wei, Hao, Mu and Lin

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Measurement of neuroendocrine factors after 28 days and 60 days of drug administration. Sham, sham group; Model, model group; Fosinopril, fosinopril group; BXYS (0.4g/kg), Buxin Yishen 0.4 g/kg treated group; BXYS (0.8 g/kg), Buxin Yishen 0.8 g/kg treated group. *P < 0.05, **P < 0.01 vs. sham group. ^#P < 0.05, ^##P < 0.01 vs. model group. ⁺P < 0.05, ⁺⁺P < 0.01 vs. fosinopril group. (A) Serum concentration of angiotensin II (Ang II) after 28 days. (B) Serum concentration of blood urea nitrogen (BUN) after 28 days. (C) Serum concentration of cyclic guanosine monophosphate (cGMP) after 28 days. (D) Serum creatinine (Scr) after 28 days. (E) Serum concentration of Ang II after 60 days. (F) Serum concentration of C reaction protein (CRP) after 60 days. (G) Serum concentration of BUN after 60 days. (H) Serum concentration of brain natriuretic peptide (BNP) after 60 days. (I) Serum concentration of Scr after 60 days.