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Mechanism of cardiac-renal connection. LAD, left anterior descending. AngII, angiotensin II. ET-1, endothelin 1. ROS, reactive oxygen species. TGF-β, transforming growth factor-β. CTGF, connective tissue growth factor. sCTGF, soluble form CTGF. LRP, low-density lipoprotein receptor-related protein. ECM, extracellular matrix.
