Table 4.
NEWS and MR-proADM values upon ED presentation and 72 h within patient subgroups
| Patient subgroups | Patient populations stratified by NEWS and MR-proADM | |||||||
|---|---|---|---|---|---|---|---|---|
| MR-proADM (nmol/L) | NEWS (points) | MR-proADM (nmol/L) | NEWS (points) | MR-proADM (nmol/L) | NEWS (points) | MR-proADM (nmol/L) | NEWS (points) | |
| < 1.77 | < 5 | ≥ 1.77 | < 5 | < 1.77 | ≥ 5 | ≥ 1.77 | ≥ 5 | |
| Population, N (%) | 425 (62.1%) | 74 (10.8%) | 100 (14.6%) | 85 (12.8%) | ||||
| Infection related 28-day mortality, N (%) | 0 (0.0%) | 10 (13.5%) | 6 (6.0%) | 14 (16.5%) | ||||
| NEWS: surviving patients | ||||||||
| ED admission (points) | 1.72 (1.29) | 2.18 (1.39) | 7.18 (1.71) | 7.97 (2.62) | ||||
| 72 h (points) | 1.54 (1.62) | 2.08 (2.26) | 4.57 (3.22) | 3.61 (2.48) | ||||
| p value | 0.182 | 0.784 | < 0.001 | < 0.001 | ||||
| NEWS: non-surviving patients | ||||||||
| ED admission (points) | NA | 2.60 (0.97) | 6.20 (1.10) | 8.36 (2.69) | ||||
| 72 h (points) | NA | 2.63 (2.07) | 4.20 (2.03) | 4.90 (3.31) | ||||
| p value | NA | 0.875 | < 0.05 | < 0.05 | ||||
| MR-proADM: surviving patients | ||||||||
| ED admission (nmol/L) | 0.88 (0.36) | 2.78 (1.16) | 1.23 (0.34) | 3.39 (1.47) | ||||
| 72 h (nmol/L) | 0.91 (0.58) | 1.80 (1.11) | 1.08 (0.50) | 2.13 (1.36) | ||||
| p value | 0.56 | < 0.001 | < 0.01 | < 0.001 | ||||
| MR-proADM: non-surviving patients | ||||||||
| ED admission (nmol/L) | NA | 3.22 (1.37) | 1.30 (0.29) | 2.77 (1.38) | ||||
| 72 h (nmol/L) | NA | 3.95 (1.02) | 1.41 (0.35) | 3.69 (2.49) | ||||
| p value | NA | 0.085 | 0.548 | 0.148 | ||||
All NEWS and MR-proADM values are expressed as mean (standard deviation). MR-proADM mid-regional proadrenomedullin, N number, NEWS National Early Warning Score