Skip to main content
. 2019 Oct 23;13:55. doi: 10.3389/fnsys.2019.00055

Figure 4.

Figure 4

Sound exposed rats demonstrate no change in GPIAS. (A) A schematic drawing of the behavioral protocol. Testing takes place in the presence of a 65 dB SPL continuous pure tone (3.5 or 7 kHz). A 30 ms silent gap prepulse preceding the startle sound (40 ms white noise burst, 120 dB SPL) reduces the magnitude of the acoustic startle response. (B) Percent GPIAS (Top), baseline startle response (Bottom Left), and comparison of startle response between Baseline (B) and Prepulse (P) trials (Bottom Right) in the presence of a 7 kHz pure tone background. Lines connect responses from the same animal. (C) Percent GPIAS (Top), baseline startle response (Bottom Left), and comparison of startle response between Baseline (B) and Prepulse (P) trials (Bottom Right) in the presence of a 3.5 kHz pure tone background. Lines connect responses from the same animal. Ns, not significant. N rats per group: 12 Naive, 12 Exposed. GPIAS, Gap-Prepulse Inhibition of the Acoustic Startle response.