Table 1.
Characteristics and comparison of patients with acute intracerebral hemorrhage according to cerebral microbleeds distribution.
| Mixed CMB (n = 111) | Strictly lobar CMB (n = 111) | Strictly deep CMB (n = 38) | |
|---|---|---|---|
| Age, mean ± SD* | 74 ± 9.8 | 73.7 ± 12.8 | 65.8 ± 14.9a |
| Male, No. (%) | 64 (57.6) | 69 (62.2) | 28 (73.7) |
| Hypertension, No. (%) | 82 (73.9) | 70 (63.1) | 31 (81.6) |
| Diabetes, No. (%) | 16 (14.4) | 18 (16.2) | 7 (18.4) |
| Previous symptomatic ICH, No. (%) | 9 (8.1) | 11 (9.9) | 2 (5.2) |
| Anticoagulant use, No. (%) | 27 (24.3) | 21 (18.9) | 5 (13.2) |
| NIHSS at admission, median [IQR]* | 6 [3–13] | 7 [4–15] | 7.5 [3–16] |
| Onset to MRI (days), median [IQR]* | 1 [0–4] | 1 [0–3] | 1 [0–3] |
| Symptomatic lobar ICH, No. (%) | 44 (39.6) | 79 (71.2)b | 5 (13.2)a |
| Presence of cSS, No. (%) | 27 (24.3) | 49 (44.1)a | 4 (10.5) |
| Presence of Disseminated cSS, No. (%) | 15 (13.5) | 27 (24.3)a | 1 (2.6) |
| CMB count, median [IQR]* | 11 [6–27] | 3 [1–9]b | 2 [1–4]b |
| Presence of chronic lobar ICH, No. (%) | 27 (24.3) | 23 (20.7) | 1 (2.6)a |
| Fazekas' WMH score/6, median [IQR]* | 4 [3–6] | 3 [2–4]b | 3 [2–5]b |
| Presence of lacune, No. (%) | 72 (64.8) | 31 (27.9)b | 16 (42.1)a |
CMB, cerebral microbleed; cSS, cortical superficial siderosis; ICH, intracerebral hemorrhage; NIHSS, National Institute of Health Stroke Score; WMH, white matter hyperintensities.
The p-values reported in the strictly lobar CMB column refer to comparison with mixed CMB. The p-values reported in the strictly deep CMB column refer to comparison with mixed CMB.
p-values were obtained via χ2 test or Wilcoxon's rank-sum test (*).
a
p < 0.05;
b
p < 0.001.