Table 1.
Representative studies of ESI-MS technologies for the non-covalent interactions between small drug molecules and DNA.
| Subjects | Ligands | Type of MS | References |
|---|---|---|---|
| Single/double-stranded DNA | EGCG | CSI-MS | Kuzuhara et al., 2006 |
| Hairpin DNA | Chelerythrine, sanguinarine | ESI-TOF MS | Bai et al., 2008 |
| DNA duplexes/triplexes | Mitoxantrone | ESI-FT-ICR MS | Wan et al., 2008 |
| Double-stranded oligodeoxynucleotides | Distamycin, hoechst 33258, hoechst 33342, berenil | ESI-MS | Wan et al., 2000 |
| Three double-stranded oligodeoxynucleotides | Five bis-β-carbolines alkaloids | ESI-FT-ICR MS | Dong et al., 2007 |
| Quadruplex DNA | Ditercalinium | ESI-TOF MS | Carrasco et al., 2002 |
| EthR6-DNA and EthR4-DNA | Ethionamide | NanoESI-Q-TOF MS | Chan et al., 2017 |