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. 2019 Oct 28;38:432. doi: 10.1186/s13046-019-1420-8

Fig. 5.

Fig. 5

Pep R in combination with anti-PD-1 treatment mediated the impairment of infiltrating immune-suppressive cells in B16-hCXCR4 tumors. Flow cytometry analysis of single-cell suspensions from digested B16-hCXCR4 tumors (n = 6/group) stained as described in Material and Methods. The histograms represent the frequencies (mean ± SEM) of %: (a) Tregs/CD45+; MDSCs/CD45+; pDC/CD45+; neutrophil/CD45+; (b) CD8+/Treg, and CD8+/MDSCs; Mann-Whitney U test P < 0.05