Table 1.

The genes involved in each module and identified DEGs.

Modules	Genes
mediumpurple2	ELANE, DEFA3, PRTN3, DEFA1, DEFA1B, MPO, DEFA4, BPI, CAMP, RNASE3, LTF, LCN2, CEL, GLE1, CTSG, PGLYRP1, MS4A3, OLR1
skyblue	RPS25, HBB, RPS27A, RPS27, RPLP2, RPS29, UBA52, RPS16, RPL41, UBA6, EEF1A1, TPT1, USP1, TRIM41, HTR2A, NRAS, CDKN1B, B2M, ACTB, TMA7, MBNL1, CREB1, H3F3A, DNM1L, CEP152, C14orf2, CDC5L, OAZ1, HBA1, RPS12, F2R, VAMP4, ORC6, SEC24B, LILRB3, EED, CLASRP, TUBD1, SUPT3H, KIAA0907, ROCK2
yellow	ISG15, OAS1, MX1, DDX58, IFIT1, RSAD2, IFIT3, IRF7, IFIT2, OAS2, IFI35, UBE2L6, MX2, SP100, HERC5, TRIM22, TRIM25, EIF2AK2, OASL, ADAR, STAT2, TRIM21, TRIM5, PML, IFIH1, CMPK2, IFI44, FBXO6, ZBP1, IFI44L, DDX60, OAS3, IFIT5, SAMD9, SAMD9L, DHX58, RTP4, PARP12, SP110, PLSCR1, HELZ2, AZI2, IFI16, PARP9, TNFSF10, TDRD7, PHF11, TNFSF13B, EPSTI1, ANKFY1, ZNFX1, LGALS9, FAM46A, USP18, NT5C3, NMI, TRAFD1, C19orf66, CHMP5, LAMP3
DEGs (between normal and infected subjects)	OTOF, IFI44L, XAF1, IFI6, EPSTI1, IFI44, SAMD9L, EIF2AK2, IFI35, OAS3, HESX1, OASL, STAT1, ISG15, MX1, DDX60, PARP9, RNF213, IFITM3, LY6E, HELZ2, FBXO18, IRF7, ADAR, RSAD2, MOV10, IFIH1, IFIT3, STAT2, FBXO6, SAMD9, SCO2, CMPK2, NEXN, H1F0, TNK2, C2, OAS2, MYOF, SP100, DHX58, CMTR1, RTP4, PARP10, SHISA5, SLC26A8, IFIT1, SPATS2L, OAS1, RNF31, GPR84, RPA4, LOC100419583, TAP1, PML, SLC24A4, IFITM1, LGALS3BP, UBE2L6, FCER1A, TOMM7, MASTL, MS4A4A, RPL13P5, SSH1, REC8, MEF2A, BST2, PHF11, ABCD1, MX2, JAK2, IL15RA, SP110, PARP12, DEFB1, SLC1A3, CCR3, BMX, TAPBP, LENG8, PLSCR1, HERC5, HIST2H2AA3, TRIM5, IRF9, PARP14, SERPING1, BATF2, TOR1B, STAB1, RTN2, PNKD, LAP3, IL37, STRADA, N4BP1, NR2C2, EEF1B2, CD1C, RN7SK, CLEC5A, GBA, LYG1, HP, GRN, CC2D2B, FCGR1B, CARD16, NCOA7, ZBP1, EPB41L3, IFI27, TRIM22, ARHGEF11, KIAA1958, MARK3, C1QC, TRIM25, MT1G, RPL7, TMPPE, MT2A, HIST2H2AC, ADRA1D, TDRD7, ZNFX1, LTB4R, ARG1, LDLR, CAPN3, SLC30A1, BRSK1, GPD2, CUX1, TYMP, AGRN, MAFB, RPL14, ZNF839, RPL23, IFIT5, SUSD1, FXYD6, ECE1, TRAFD1, EIF3L, RIMBP3, RPL5, AXL, DNASE2, NT5C3A, CNIH1, RGL1, SUOX, LGALS9, YEATS2, MICB, MTHFD2, EIF3F, HLA-DRA, NELL1, DTX3L, TRIM14, ANKRD22, HOOK3, IL1RN, PIWIL4, TMEM51, CAPN2, PRAM1, TRIM6, TCTN1, SPPL2A, MTF1, RPL37A, FCGR1A, NTNG2, AIM2, CTSL, GORASP1, CCR1, C3AR1, ATP8B4, EEF1G, ZCCHC2, REXO1, SLC9A1, SOCS3, RPS27A, HTR3A, RAB27A, UBA7, PAQR6, MMP9, ZNF341, TAOK2, CEP152, EXOG, FLVCR2, CTGF, HIST1H2BD, TRIM38, MAP 3K7CL, CDC25C, SLC16A6, PAG1, HGD, VDR, TMEM62, DDX58 RPL4 TIAF1 ANKFY1 ADAM9 RPL23AP32 MT1A ADAP2 FBL FOXD4L1 IFIT2 ATF3 RPS9 TCN2 MAFG MDM2 OLIG3 CHMP5 LMNB1 DPH5 AGFG1 RIPK3 LGALS9C IFI16 MB21D1 MERTK SIGLEC16 CKAP4 DPRXP4 BAZ1A DISC1 SCARB2 CDKN1A TMEM110 WARS TXN APOL2 SNX20 GPR155 CRTAP TXNDC12 RPL31 TRIM21 EIF4G3 TET2 CTSD CXCR2P1 FFAR3 INPP4A RHOT1 C12orf57 LGALS8 MED15 SRGAP2 RPL3 ATL3 SLC9A8 TMOD3 GYG1 HVCN1 ASGR2 FAM209B GCH1 OGFR NELL2 SLC27A3 STBD1 NBEAL2 NDST1 TRIM69 RNF19A CD36 VNN1 CEPT1 LHX6 SLC22A18 TBC1D2 HIST2H2AB ITIH4 GLS PTP4A1 MYD88 RPL13A RPS14 PLEC UGGT2 RBM43 GBP1 SYT17 FAM46A SORT1 ADAMTSL4 RPL23AP64 USP18 ATP11C C1QB ARSA EXT1 MR1 OPLAH RPS3 BCL2L11 HK3 LOXL3 MCMBP WWP2 CD177 MCEMP1 TRPM4 SLC6A12 ABCC10 RPL21 SLITRK4 CALML4 STX16 B4GALT5 ARID3A VAMP5 DNAJC5 YIPF1 DIAPH