Table 1.
Association between KDM4C expression and clinicopathological variables of CRC patients
| Variables | Low KDM4C expression (n = 67) | High KDM4C expression (n = 57) | P |
|---|---|---|---|
| n (%) | n (%) | ||
| Age | |||
| > 65 | 13 (19.40) | 10 (17.54) | 0.8210 |
| ≤ 65 | 54 (80.60) | 47 (82.46) | |
| Gender | |||
| Male | 39 (58.21) | 39 (68.42) | 0.2673 |
| Female | 28 (41.79) | 18 (31.58) | |
| Tumor site | |||
| Rectum | 37 (55.22) | 36 (63.16) | 0.4642 |
| Colon | 30 (44.78) | 21 (36.84) | |
| Tumor differentiation | |||
| Well | 20 (29.85) | 19 (33.33) | 0.7019 |
| Moderate + Poor | 47 (70.15) | 38 (66.67) | |
| TNM stage | |||
| Stage II | 35 (52.23) | 12 (21.05) | 0.0004** |
| Stage III | 32 (47.77) | 45 (78.95) | |
| Lymph vascular invasion | |||
| Positive | 44 (65.67) | 42 (73.68) | 0.4347 |
| Negative | 23 (34.33) | 15 (26.32) | |
| Perineural invasion | |||
| Positive | 52 (77.61) | 46 (80.70) | 0.8253 |
| Negative | 15 (22.39) | 11 (19.30) | |
| Liver metastasis | |||
| Positive | 9 (13.43) | 22 (38.60) | 0.0017** |
| Negative | 58 (86.57) | 35 (51.40) | |
| Lung metastasis | |||
| Positive | 1 (1.49) | 8 (14.04) | 0.0114* |
| Negative | 66 (98.51) | 49 (85.96) | |
*, P < 0.05; **, P < 0.01