Figure 4.
Knockdown of MALAT1 Inhibited GBM Progression and ZHX1 Expression In Vivo
(A) Representative axial MR images and H&E staining of xenograft GBM tumors in normal control, miR-199a inhibitor, and MALAT1-KD groups. (B) Tumor volume in normal control, miR-199a inhibitor, and MALAT1-KD groups. (C) Comparative survival of mice bearing normal control, miR-199a inhibitor, and MALAT1-KD. (D and E) Western blot analysis (D) and densitometric quantification (E) of ZHX1 in tumor tissues collected from nude mice injected with normal control, miR-199a inhibitor, and MALAT1-KD. *p < 0.05.