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. 2019 Sep 17;18:388–399. doi: 10.1016/j.omtn.2019.09.005

Figure 5.

Figure 5

MALAT1 Promoted ZHX1 Expression via miR-199a in GBM Cells

(A and B) qRT-PCR and western blot analysis of ZHX1 mRNA (A) and protein (B) expression levels in T98G and U251 MALAT1-KD cells. (C) Knockdown of MALAT1 increased miR-199a levels in T98G and U251 cells. (D and E) Ectopic miR-199a expression decreased ZHX1 mRNA (D) and protein (E) expression levels in T98G and U251 cells. (F) ZHX1 protein levels in T98G and U251 cells transfected with empty vector, or MALAT1-shRNA, or miR-199a inhibitor or both. *p < 0.05.