TABLE 2.
Spearman-rank correlations of preexisting (day –2) anti-gC Ig and IgG4/7 antibodies in nasal secretion and serum with protection from EHV-1 infection outcomes
Parameter | Nasal anti-gC Ig | Nasal anti-gC IgG4/7 | Serum anti-gC Ig | Serum anti-gC IgG4/7 |
---|---|---|---|---|
Fevera | R = –0.622 | R = –0.539 | R = –0.747 | R = –0.767 |
P = 0.0012 | P = 0.0065 | P < 0.0001 | P < 0.0001 | |
Clinical diseaseb | R = –0.443 | R = –0.404 | R = –0.482 | R = –0.465 |
P = 0.0304 | P = 0.0503 | P = 0.0172 | P = 0.0222 | |
Virus sheddingc | R = –0.806 | R = –0.748 | R = –0.816 | R = –0.805 |
P < 0.0001 | P < 0.0001 | P < 0.0001 | P < 0.0001 | |
Cell-associated viremiad | R = 0.670 | R = 0.607 | R = 0.759 | R = 0.758 |
P = 0.0001 | P = 0.0017 | P < 0.0001 | P < 0.0001 |
Body temperature at 60 h p.i. (fever peak).
Clinical score on day 4 p.i.
Virus isolation in nasal secretion (PFU) on day 2 p.i.
EHV-1 real-time PCR for the gB gene (cycle threshold [CT]) in PBMC on day 5 pi.