FIG 3.

Inhibitory activity of GPI-anchored peptides in transduced TZM-bl cells against HIV-1, HIV-2, and SIV isolates. The inhibition of GPI-2P23, GPI-C34, and GPI-4B10 on two HIV-1 pseudoviruses (NL4-3 and JRCSF), two replicative HIV-2 isolates (ROD and ST), two SIV pseudoviruses (mac239 and smmPBj), and VSV-G was determined. The transduced cells were sorted so as to express the cognate GPI-anchored peptide in close to 100% of the cells. Error bars represent the means ± standard errors of the means (SEM) from three independent experiments with triplicate samples. Mock, parental TZM-bl cells; GPI-2P23, GPI-2P23-transduced TZM-bl cells; GPI-C34, GPI-C34-transduced TZM-bl cells; GPI-4B10, GPI-4B10-transduced TZM-bl cells.