Fig. 3.

In vivo assessment of venous and arterial TEVGs. Serial ultrasound measurements of graft and adjacent native inferior vena cava or abdominal aortic segments were performed over 10 weeks. (A) Plot comparing average luminal diameters of implanted TEVGs normalized to the adjacent vessel diameter as acquired by transabdominal ultrasound. There was no significant change in luminal diameter over this period between groups. However, after 4 weeks arterial grafts demonstrated progressive dilation and venous grafts progressive narrowing. (B) In situ image of an electrospun PCLA vascular graft 6 weeks after surgical implantation in the arterial circulation compared with a ruptured arterial TEVG 14 weeks after implantation. In both images: A) Proximal aorta. B) Electrospun PCLA graft. C) Distal aorta. Arrows indicate observed areas of electrospun TEVG degradation.