. 2019 Oct 23;2(10):e1913951. doi: 10.1001/jamanetworkopen.2019.13951

Table 1. Model Inputs.

Variable	Cohort Input (Simulation Range)^a	Source
Cost per hour of observation, $^b	286.92 (100-500)	Blumenthal et al, 2018,²⁸ and Bureau of Labor Statistics²⁹
Indirect costs per hour, $^b	27.77 (0-50)	Bureau of Labor Statistics³⁰
Extended observation, h	6 (6-24)	Kim et al, 2019³¹
Short observation, h	1
Biphasic anaphylaxis negative predictive value at 1-h observation, %	95 (95-99)
Biphasic anaphylaxis negative predictive value at ≥6-h observation, %	97.3 (97.3-99)
Biphasic anaphylaxis case fatality, %	0.33 (0.25-0.33)	Ma et al, 2014¹³
Fatality risk reduction	10-fold	Modeling assumption (sensitivity range 10- to 1000-fold)

^{^a}

The cohort input also served as the mode for the triangular distribution used in simulation.

^{^b}

Costs are shown in 2019 US dollars.