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- Plasma and heart concentrations of Cpd 38 after 5-min i.v. administration in anesthetized mongrel dogs (values are mean ± SD with n = 3 per group).
| Dose | Sampling time | Total plasma concentration | Heart concentration | ||
|---|---|---|---|---|---|
| mg/kg | min | μg/mL | μM | μg/g | μM |
| 10 | 10 | 23.4 ± 2.83 | 64.5 | Not taken | Not taken |
| 60 | 10.1 ± 0.769 | 27.8 | 14.6 ± 2.70 | 40.2 | |
