Fig. 1.
Schematic of the blood samples collected during the study (time 0, 1, 2, 4 and 16–24 h) post bivalirudin administration. A. Inhibition of platelet aggregation was compared at early 2 min and final 15 min time point for platelets stimulated with agonist during the study (B) (time 0, 1, 2, 4 and 16–24 h). Patients were pretreated with Clopidogrel (n = 12) or Prasugrel (n = 12). PRP was prepared from patients at baseline (time 0) and at 1, 2, 4 and 16 h after discontinuation of bivalirudin. Platelet aggregometry was performed at 37 °C.