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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Thromb Res. 2019 Feb 13;177:59–69. doi: 10.1016/j.thromres.2019.01.017

Fig. 6.

Fig. 6.

Effect of PAR4 Thr120 vs Ala120 Genetic Variation in Platelet Aggregation and Contribution of P2Y12. Platelet aggregation was compared at final 15 min time point for platelets stimulated with 160 μΜ AYPGKF (A, B), 5μΜ SFLLRN (C.D) and 5 μg/mL of collagen (E,F). Data are reported as mean ± SD (n = 8–9 PAR4-AA, n= 2–3 PAR4-TA/TT). PAR4-AA: PAR4 genotype homozygous Ala120; PAR4-TA/TT: PAR4 genotype for the hyperactive Thr120 (TA-homozygote and TT heterozygote). Prasugrel (black), Clopidogrel (white).