Table 1.
Ki-67 index (%) | Mitotic index | |
---|---|---|
Well-differentiated NENs | ||
NET G1 | <3 | <2/10 HPF |
NET G2 | 3-20 | 2-20/10 HPF |
Poorly differentiated NENs | ||
NEC G3 | >20 | >20/10 HPF |
Small cell type | ||
Large cell type | ||
MINEN/MENEN |
Source: Adapted from WHO Classification of Tumors of Endocrine Organs, Fourth edition (2017).
Abbreviations: HPF, high-power field; MINEN/MENEN, mixed endocrine non-endocrine neoplasms; NEC, neuroendocrine carcinoma; NEN, neuroendocrine neoplasm; NET, neuroendocrine tumor; WHO, World Health Organization.