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. 2019 Oct 24;12:1179551419884058. doi: 10.1177/1179551419884058

Table 1.

2017 WHO Classification of GI Neuroendocrine Tumors.

Ki-67 index (%) Mitotic index
Well-differentiated NENs
 NET G1 <3 <2/10 HPF
 NET G2 3-20 2-20/10 HPF
Poorly differentiated NENs
 NEC G3 >20 >20/10 HPF
  Small cell type
  Large cell type
  MINEN/MENEN

Source: Adapted from WHO Classification of Tumors of Endocrine Organs, Fourth edition (2017).

Abbreviations: HPF, high-power field; MINEN/MENEN, mixed endocrine non-endocrine neoplasms; NEC, neuroendocrine carcinoma; NEN, neuroendocrine neoplasm; NET, neuroendocrine tumor; WHO, World Health Organization.