Figure 7.

Longitudinal PC-CT In Vivo Imaging of Liver Tumor Dynamics in Alb-R26^Met Mice Once Treatment with Targeted Drug Combination Was Discontinued

Examples of longitudinal monitoring of liver tumor growth in Alb-R26^Met mice from the last day of treatment (D40) over time (D50, D60, D70). M7-T2 tumor started to grow (top), whereas M7-T1 tumor growth was not observed and a high-contrasted area persisted over time. For each day of monitoring, transversal (top), coronal (left bottom), and sagittal (right bottom) slices are shown. The red arrows indicate the corresponding tumor. Note that these two tumors recorded in the same mouse were both sensitive to the treatment, although the M7-T2 relapsed, whereas the M7-T1 did not.