Figure 8.
Qualitative and Quantitative PC-CT Measurements of Alb-R26Met Liver Tumors in Mice after Treatment with Targeted Drug Combinations
(A) Images corresponding to transverse slices at tumor maximum diameter of five independent tumors at the end of treatment (D40) and 30 days later (D40 + 30).
(B) 3D reconstructions of tumor volumes at D40 (end of treatment) and after 30 days (D40 + 30). On the left, tumor (gray) and high-contrasted (orange) volumes are reported. On the right, images correspond to tumor volumes (gray).
(C) Graphs reporting longitudinal imaging measurements of tumor (gray) and high-contrasted (orange) volumes at D0 (before treatment), at the end of treatment (D40), and during the following 30 days. Complete regression was observed for M7-T1 tumor, whereas regrowth occurred for the other four tumors, although with a variable speed and kinetics. Images of tumors at D40, already shown in Figure 5A, are also shown here for direct comparison with tumor images at D40 + 30.