Platelet (PLT) counts and mean platelet volume (MPV) in the blood after irradiation and/or hindlimb unloading (HLU) at 4 or 30 days post-unloading (11 and 37 days post-irradiation, respectively). Three-Way ANOVA: †=P<0.05, IR x HLU interaction. T =P<0.1, IR x HLU interaction. Post hoc Tukey test: # =p<0.05, TT =P<0.1. Note the strong HLU dependence at 4 days post treatment, but smaller influence of radiation for PLT counts.