Figure 3.

Deep profiling of CD56^dim and CD56^bright NK cells in non-pregnant and pregnant women from validation cohort. (A,B) Markers predictive of CD56^dim NK cells in control vs. pregnant women in validation cohort were assessed by GLM with bootstrap resampling. The markers are listed on the y-axis and the x-axis represents the log-odds that the marker expression levels predict the outcome (control on the left vs. pregnancy on the right). Summary data are depicted, showing the 95% confidence interval. Markers in which the bar does not cross zero are significantly predictive of one state vs. the other. (C) Represents the linear discriminant analysis (LDA) for CD56^dim NK cells between non-pregnant, pregnant and post-partum samples from validation cohort. (D,E) Markers predictive of CD56^bright NK cells in control vs. pregnant women in validation cohort were assessed by GLM with bootstrap resampling. The markers are listed on the y-axis and the x-axis represents the log-odds that the marker expression levels predict the outcome (control on the left vs. pregnancy on the right). Summary data are depicted, showing the 95% confidence interval. Markers in which the bar does not cross zero are significantly predictive of one state vs. the other. (F) Represents the linear discriminant analysis (LDA) for CD56^bright NK cells between non-pregnant, pregnant and post-partum samples from validation cohort.