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. Author manuscript; available in PMC: 2019 Oct 30.
Published in final edited form as: Chem Phys Lipids. 2019 Jan 29;219:28–35. doi: 10.1016/j.chemphyslip.2019.01.009

Fig. 3. 4F prevents the oxidative modification of apoA-I.

Fig. 3.

Tryptic fragments of apoA-I were generated by the addition of hypochlorite (OCl−) and eluted by chromatography. The fragment VQPYLDDFQK containing a chlorinated tyrosine residue is depicted in Panel A. Addition of 4F to this reaction mixture significantly reduced formation of this oxidized product. Levels of unmodified apoA-I were negligible. The MS spectrum for the chlorinated VQPYLDDFQK fragment is shown in Panel B. This fragment displays an isotopic distribution with double-charged tryptic fragments.