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. 2019 Oct 23;10:988. doi: 10.3389/fgene.2019.00988

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Copyright © 2019 Li, Hu, Wang, Deng, Yang, Hu, Li and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Screening of significantly differentially expressed (DE) mRNAs and miRNAs among either in granulosa or theca layers of geese follicles at different developmental stages. Time-series cluster analysis for the expression profiling of DE mRNAs and miRNAs in the granulosa layer (A, B) and theca layer (C, D). Note that the transition period for follicles from 8–10 mm in diameter to F5 was used for follicle selection. Profiles 2, 3, 5, 7, ii, and iv indicated those DE mRNAs or miRNAs with unchanged expression before follicle selection, following significant fluctuation during follicle selection. Profiles 1, 4, 6, i, and iii represent DE mRNAs or miRNAs with significantly changed expression throughout follicle development.