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. 2019 Oct 23;10:988. doi: 10.3389/fgene.2019.00988

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Copyright © 2019 Li, Hu, Wang, Deng, Yang, Hu, Li and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways of differentially expressed (DE) mRNAs from different time-series modules in either granulosa or theca layers. (A, B) Top 20 KEGG pathways of DE mRNAs from profile 3 (A) and profile 2 (B) in the granulosa layer. Five pathways of tight junction, adherens junction, cell adhesion molecules, ECM–receptor interaction, and focal adhesion were identified in profile 3 (A). The two pathways of fat digestion and absorption and glycerolipid metabolism were contained in profile 2 (B). (C, D) Top 20 KEGG pathways of DE genes of profile 5 (C) and profile 7 (D) in the theca layer.