Table 2.
Association between age and mortality in ARDS patients (mediation step 1)
| Crude odds ratio [95% CI] | p value | Adjusted odds ratio [95% CI]‡ | p value | GOF p value | |
|---|---|---|---|---|---|
| 90-day mortality | |||||
| Young adults | Reference | NA | Reference | NA | 0.153 |
| Middle-aged adults | 1.3 [0.9, 2.0] | 0.159 | 1.5 [1.0, 2.3] | 0.078 | |
| Elderly | 1.7 [1.2, 2.6] | 0.008 | 2.1 [1.4, 3.4] | 0.001 | |
| 30-day mortality | |||||
| Young adults | Reference | NA | Reference | NA | 0.081 |
| Middle-aged adults | 1.1 [0.7, 1.7] | 0.740 | 1.2 [0.8, 1.9] | 0.469 | |
| Elderly | 1.3 [0.8, 2.0] | 0.240 | 1.5 [0.9, 2.4] | 0.096 | |
| 1-year mortality | |||||
| Young adults | Reference | NA | Reference | NA | 0.716 |
| Middle-aged adults | 1.5 [1.0, 2.2] | 0.035 | 1.7 [1.1, 2.6] | 0.016 | |
| Elderly | 2.0 [1.4, 3.0] | 0.000 | 2.4 [1.6, 3.8] | 0.000 | |
Data is presented as odds ratio’s (OR) with a 95% confidence interval [CI]. ‡Adjusted for ethnic background, gender, admission type, readmission, direct hit for ARDS, Charlson Comorbidity Index, APACHE-IV score adjusted for age, immunodeficiency, tidal volume per predicted body weight, and positive end-expiratory pressure. A p value < 0.05 was considered as statistically significant. GOF goodness of fit, omnibus test, a p value of < 0.05 is considered as a lack of fit. NA not applicable