Figure 1.
The symbol “√” indicates that a pill was taken on a given day; “-” indicates no pill taken. Adherence pattern “A” represents 100% adherence, while patterns “B”, “C”, “D” and “E“ represent varying distributions of the same number of missed doses (18/28, or 36%). The final three columns show the average adherence, the number of ≤72-hour interruptions, and the percentage of days when the running average adherence was <10% (See Appendix Table 4a and 4b for further details). For simplicity’s sake, we assume perfect adherence prior to and after these 28 days.