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. 2019 Oct 29;10:4926. doi: 10.1038/s41467-019-12931-x

Fig. 3.

Fig. 3

Reward and goal value dissociate across the striatum’s dorsal-ventral axis. a Whole brain results for relative goal value (blue) and overall reward value (green), thresholded at voxelwise p < 0.001 and cluster-corrected p < 0.05. Despite being correlated with activity in our a priori value network ROI, overall goal value did not survive the whole-brain threshold used for these follow-up exploratory analyses. b To interrogate our findings across regions of striatum, we selected independent bilateral ROIs previously used as seeds for distinct resting-state networks:49 Dorsal Caudate (dark orange; [x, y, z] = ±12, 10, 8), Ventral Striatum, superior (orange; ±8, 10, 1), and Ventral Striatum, inferior (yellow; ±10, 11, −9). c Mixed-effects regression coefficients across these ROIs demonstrate a dorsal-ventral dissociation, with dorsal regions more sensitive to overall reward value and the ventralmost region more sensitive to relative goal value. Error bars show standard error of the mean. **p < 0.01, ***p < 0.001