Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 29;9:15554. doi: 10.1038/s41598-019-52171-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Activation of whole-cell Cl⁻ currents evoked by MSN, but not by KYN, TON, or DIO, in HEK/CFTR cells under a conventional whole-cell patch-clamp. (a) Representative responses of whole-cell currents to MSN. Left panel: Time courses of changes in whole-cell currents before and after application of MSN (400 μg/ml) during application (every 10 s) of ramp pulses of −100 to +100 mV from a holding potential of 0 mV. (b) Corresponding I-V relationships recorded at time points a and b in the left panel. (c) Peak current densities recorded at +100 mV before (control) and after (+herbal component) application of each herbal component (400 μg/ml). Each column represents the mean ± S.E.M. (n = 5–10). *P < 0.05 compared with the control value.