Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 29;9:15469. doi: 10.1038/s41598-019-51939-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Hyperosmotic upregulation of TonEBP target gene expression is not affected by inhibition of primary cilia formation in NP cells. (a–c) mRNA levels of TonEBP targets, AR/Akr1b1, SMIT/Slc5a3 and TauT/Slc6a6, showing that stable silencing of Ift88 does not affect their response to hyperosmotic stimuli (550 mOsm/kg H₂O) (n ≥ 5). (d–f) mRNA levels of AR/Akr1b1, SMIT/Slc5a3 and TauT/Slc6a6 demonstrate that Kif3a knockdown also does not influence hyperosmotic upregulation of these genes (n ≥ 3). Data are represented as scatter plots (mean ± SEM). ns = not significant. One-way ANOVA or Kruskal-Wallis test with Sidak’s or Dunn’s multiple comparison test was used based on the distribution of the data to determine statistical significance.