Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Oct 29;6:237. doi: 10.1038/s41597-019-0255-7

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the metadata files associated with this article.

PMC Copyright notice

Fig. 4 — Example drug combination plots for drug combinations found to be highly synergistic according to Bliss excess and p-value. (a) The graphs show viability data with standard deviation for COLO 205 cells tested Doramapimod (BI) and Akt Inhibitor VIII (AK) and UACC-62 cells tested with BI-D1870 (D1) and SF1670 (SF) in the primary screen. (b) The graphs show viability data with standard deviation for SF-295 cells treated with drug combinations Doramapimod (BI) - PI-103 (PI) and BI-D1870 (D1) - PI, and A498 cells treated with BI - PI in the primary and secondary screen. The data is normalised to DMSO control.