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. 2019 Oct 29;9:15510. doi: 10.1038/s41598-019-52029-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in the mean flow velocity in sleep monitoring: Representative cases. Transcranial Doppler monitoring during short-term non-REM sleep in a 33-year-old woman (upper panel), a 65-year-old man (middle panel), and a 60-year-old man (lower panel) showed a marked amplification of the periodic patterns in the peak systolic velocity, mid-diastolic velocity, and mean flow velocity graphs with a period of approximately 50 s, which appeared within a few minutes after the onset of sleep.