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. 2019 Oct 29;9:15458. doi: 10.1038/s41598-019-51865-8

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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LXRβ regulates immune response and glycerophospholipids accumulation in glioma tumor initiating cells. (A) Gene Set Enrichment of Gene Ontology Biological Processes in TS600 crNT dense vs sparse compared to crLXRb-1 dense vs sparse. Pink sets are enriched in crNT cells and blue are enriched in crLXRb-1. (B) Leading edge analysis of genes shared between enriched gene sets for crNT (pink bars) and crLXRb-1 (blue bars) in (A). (C) crNT and crLXRb-1 cells were subjected to lipidomics profiling, then enrichment analysis was performed using LIPID MAPS categories. The category “Glycerophospholipids” is shown. (D) Enrichment analyses of the LIPID MAPS mainclass subsets of “Glycerophospholipids”. The mainclasses “Glycerophosphoinositols” and “Glycerophosphoethanolamines/Glycerophosphocholines (GPE/GPC)” is shown.