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. 2019 Oct 30;2019(10):CD004659. doi: 10.1002/14651858.CD004659.pub3

Pergar 1987.

Methods Double‐blind placebo‐controlled trial
Participants 300 women with history of idiopathic fetal growth. Fetal growth retardation must be <10 percentile of Lubchenco et al. Therapy began at 15 to 17 weeks' gestation.
Excluded: Presence of chronic disease, allergy to dipyridamole, uterine or malformation, secondary hypertension, early fetal death in a previous pregnancy, current use of anti inflammatory drugs or anticoagulants
Interventions Exp: dipyridamole 225mg/day
Control: placebo
Outcomes Babies: birth weight related to GA
Notes Conducted by doctors from 50 hospitals throughout France and Belgium.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Study appears to be randomised; however, French translation needed to confirm this
Allocation concealment (selection bias) Unclear risk French translation needed to determine if allocation was concealed.
Blinding (performance bias and detection bias) 
 All outcomes Low risk Trial is double‐blind placebo‐controlled.
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk French translation needed to judge this.
Selective reporting (reporting bias) Unclear risk French translation needed to judge this.
Other bias Unclear risk No imbalance in baseline characteristics. French translation needed to determine if there may be any other sources of bias.