USA 1997.

Methods	Quote: "Randomly assigned", no further information.
Participants	19 women with antiphospholipid antibodies and </= 2 previous miscarriages with no other antiphospholipid antibody‐related complications. Gestational age not described. Excluded: previous thrombosis, early onset PE, thrombocytopenia.
Interventions	Exp: aspirin 81 mg/day throughout pregnancy. Control: usual care.
Outcomes	Babies: fetal death; SGA (< 5th percentile); fetal distress at term (not defined).
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Quote: "Randomly assigned", no further information.
Allocation concealment (selection bias)	Unclear risk	Quote: "Randomly assigned", no further information.
Blinding (performance bias and detection bias) All outcomes	High risk	Blinding not mentioned but aspirin was compared to usual care (not placebo) so likely not blinded.
Incomplete outcome data (attrition bias) All outcomes	Low risk	Attritions/exclusions not explicitly reported in article but data in Table I indicates that there were none.
Selective reporting (reporting bias)	Unclear risk	Protocol not available and outcomes not clearly specified in methods section or elsewhere. Therefore, insufficient information to judge.
Other bias	Unclear risk	Baseline characteristics: quote: "The patients' obstetric histories… and antiphospholipid antibody test results are summarised in Table I. None of the differences between groups was statistically significant." However, demographic details of groups (e.g. age, weight, etc) not provided.