Table 2.
Number and entity of index tumors per volume. Bone sarcoma and carcinoma were frequent in unirradiated controls and non-irradiated volumes (NIRVs) of irradiated rats while lymphoma and soft tissue sarcoma were frequent in combined irradiated low-dose volume, bordering high-dose volume and high-dose volume (LDV/BHDV/HDV).
| Volume | BSA | CA | SSA | BT | BC | LY | MM | ND | Total | |
|---|---|---|---|---|---|---|---|---|---|---|
| ♀ | ♂ | |||||||||
| AN/CBCT | 13 | 4 | 1 | 2 | 2 | — | — | 5 | 14 | 13 |
| NIRV 3 × 5 Gy/3 × 8 Gy combined | 9 | 4 | 1 | 1 | 1 | — | — | 8 | 11 | 13 |
| VMAT 3 × 5 Gy LDV/BHDV/HDV | 3 | 1 | 2 | — | — | 3 | 1 | — | 5 | 5 |
| AP/PA 3 × 5 Gy LDV/BHDV/HDV | — | 1 | 2 | — | — | 4 | — | — | 4 | 3 |
| VMAT 3 × 8 Gy LDV/BHDV/HDV | — | — | 1 | — | — | 2 | 1 | — | 2 | 2 |
| AP/PA 3 × 8 Gy LDV/BHDV/HDV | 2 | 1 | 6 | — | — | 3 | — | — | 7 | 5 |
| Total | 27 | 11 | 13 | 3 | 3 | 12 | 2 | 13 | 43 | 41 |
Abbreviations: BSA, bone sarcoma; CA, carcinoma, SSA, soft sarcoma; BT, brain tumor; BC, breast cancer; LY, lymphoma; MM, malignant mesothelioma; ND, not determined; NIRV, non-irradiated volume; Gy, Gray; AN, anesthesia only controls; CBCT, cone-beam computed tomography controls; VMAT, volumetric-modulated arc therapy; AP/PA, anterior-posterior/posterior-anterior irradiation; LDV/BHDV/HDV, low-dose volume, bordering high-dose volume, and high-dose volume combined (planned volume).