Table 2.
Platelet and WBC variable distribution in the Moli-family cohort
| Variable | Moli-family (n = 605) |
|---|---|
| Platelet measurements | |
| Platelet count, 109/L | 249.4 ± 60,6 |
| Mean platelet volume, fL | 8.59 ± 0.98 |
| Plateletcrit, % | 0.21 ± 0.05 |
| Platelet distribution width, % | 16.4 ± 0.6 |
| Soluble P-selectin, μg/L | 82.7 ± 38.0 |
| Platelet P-selectin, % | 2.76 ± 3.65 |
| Platelet/monocytes aggregates, % | 7.24 ± 8.62 |
| Platelet/PMN aggregates, % | 4.32 ± 5.02 |
| Inflammation measurements | |
| White blood cell count, 109/L | 6.19 ± 1.52 |
| Neutrophils, % | 61.0 ± 8.0 |
| Lymphocyte, % | 32.0 ± 7.0 |
| Neutrophil/lymphocyte ratio | 2.08 ± 0.83 |
| Monocyte, % | 7.0 ± 2.0 |
| Red blood cell, 1012/L | 4.89 ± 0.5 |
| Platelet/lymphocyte ratio | 135.9 ± 47.6 |
| INFLAscore* | − 0.23 ± 5.59 |
| C-reactive protein, mg/mL | 1.7 ± 1.74 |
| Monocyte L-selectin, % | 10.4 ± 7.2 |
| PMN L-selectin, % | 25.7 ± 21.3 |
| Monocyte CD11b, % | 51.5 ± 24.1 |
| PMN CD11b, % | 44.0 ± 25.1 |
*INFLAscore is calculated as follows: 10 tiles of each biomarker levels (CRP, WBC, platelets, G/L ratio) were generated. For all four components, being in the highest deciles (7 to 10) gave a score which increased from 1 to 4, while being in the lowest deciles (1 to 4) was negatively scored from − 4 to − 1. Being in the deciles 5 or 6 got zero points. In such a way, the INFLA-score ranges from − 16 to 16 and comes up as the sum of the four biomarkers. An increase in the score represented an increase in low-grade inflammation intensity