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. 2019 Oct 30;19:1419. doi: 10.1186/s12889-019-7677-1

Table 1.

Data abstraction table

Author and Year Country Study Design Study Population
and Sample Size
Policy/intervention type Length of intervention/ policy Stunting reduction (yes/no) Impact on stunting Economic indicators Impact on economic indicators
Amouzou, A. et al., 2012 [32] Niger Case Study

Children under 5 in Niger

n = N/A

Multisectoral programmes and policies focused on maternal, newborn and child health On-going since 1996 Yes Decrease in stunting prevalence for children aged 24–35 months from 67 to 54% in 2009 (13% reduction) Childhood mortality 5.1% annual reduction in U5MR with 10% of this reduction attributed to reductions in stunting prevalence.
Huicho, L. et al., 2016 [37] Peru

Children under 5 in Peru

n = N/A

Policies and programmes for reducing poverty, reforming the health sector, and improving reproductive health, nutrition and maternal and child health. On-going since 2005 Yes

Stunting prevalence decreased from 30% in 2000 to 17.5% in 2013

Calculate % reduction

Under 5 mortality decreased by 58% (from 2000 to 2013).
Kanyuka, M. et al., 2016 [29] Malawi Children under 5 in Malawin = N/A Policies, programmes and funding allocation that aimed to increase coverage of high-impact interventions that addressed the main causes of childhood mortality On-going since 1990’s Yes Stunting deceased by 11.1% between 2000 and 2013 Under 5 mortality fell from 247 deaths/1000 livebirths to 71/1000 from 1990 to 2013 with 8.6% of this reduction attributed to reductions in stunting prevalence.
Ruducha, J., 2017 [26] Ethiopia

Children under 5 in Ethiopia

n = N/A

Policies and programmes for reducing poverty and improving agricultural productivity, food security, water supply, and sanitation. On-going since before 2000’s Yes Stunting prevalence decreased from almost 60% in 2000 to 40% in 2014 (20% decrease) Under 5 mortality decreased from 205 deaths/1000 livebirths in 1990 to 64 deaths/1000 livebirths in 2013 with 44% for this reduction attributed to reductions in stunting prevalence.
Andersen, T. et al., 2015 [38] Peru Prospective cohort study

Children 7–8 in Peru

n = 1960

Conditional Cash Transfer programme (CCT) “Juntos” On-going since 2005 Yes Only in boys exposed to CCT for 2y or more: 0.43-point increase in HAZ score [95% CI: 0.09–0.77], p < 0.01) Language development and school achievement No significant effects observed.
Fernald, L.C.H. et al., 2008 [39] Mexico Retrospective cohort study Children 24–68 months old who were exposed to “Opportunidades” their whole lives n = 2449 children Conditional Cash Transfer programme “Opportunidades” On-going since 1998 Yes

Doubled cash transfer associated with:

0.2 [95%CI: 0.09–0.30], p < 0.0001) increase in HAZ score, 10% 0(p < 0.0001) decrease in stunting

Cognitive, motor and language development

Doubled cash transfer associated with:

0.06 (p = 0.67) points higher in motor skill and 1.15 (p = 0.001) higher in endurance; 0.12 (p = 0.002) point higher in long-term memory, 0.13 (p < 0.0001) points higher in short-term memory and 0.08 (p = 0.02) point higher in visual integration;: 0.18 (p < 0.0001) higher language score

Fernald, L.C.H. et al., 2009 [40] Mexico Retrospective cohort study

Children 8–10 years who were part of an early vs. late (18 mo. difference) introduction to Conditional Cash Transfer programme “Opportunidades”

n = 1793

Conditional Cash Transfer programme “Opportunidades” On-going since 1998 Yes

Additional 18 mo. Of CCT for children of uneducated mothers:

1.5 cm (p = 0.029) increase in HAZ/ 0.23-point HAZ increase (95% CI = 0.23–0.44)

Cognitive, language and socioemotional development Early vs. late treatment: Reduced behavioural problems (mean score − 0·09 vs. 1·03 (p = 0·0024)
Hoddinnott, J. et al., 2008 Guatemala Retrospective Cohort Study

Adults 25–42 exposed to supplementation trial from ages 0 to 7

n = 1338

nutritional supplementation (protein supplementation beverage “atole”) 8 years Yes

- Stunting to < 20% (from baseline of 45%)

-2.4 cm (p < 0.005) increase in length of children at 3 years of age

Annual income, hours worked, average hourly wages

For exposure at 0–24 months only:

0.665 US$/h (p = 0.009) higher

Hoddinott, J. et al., 2013 Guatemala Retrospective cohort study

Adults 25–42 exposed to supplementation trial from ages 0 to 7

n = 1338

Nutritional supplementation (protein supplementation beverage “atole”) 8 years Yes - Stunting to < 20% (from baseline of 45%)-2.4 cm (p < 0.005) increase in length of children at 3 years of age Schooling-related outcomes, health outcomes, labor market outcomes

1 SD improvement in HAZ leads to:

0.78 (p = 0.003) increase in highest grade attained, 0.28 (p = 0.003) increase in reading score, 0.25 increase in non-verbal cognitive ability (0.002); 5 (p = 0.003) increase in hand strengthBeing stunted at 24 mo. leads to: leaving school 3.14 (p = 0.026) years younger, Achieving 4.64 (p = 0.004) less school grades, 1.26 (0.013) lower reading score, 1.12 (p = 0.006) lower nonverbal cognitive ability score, 22 point (p = 0.008) lower hand strength, 41% (0.017) lower likelihood of being skilled laborer or white collar worker

Kinra, S. et al., 2008 [41] India Retrospective cohort study 13–18 year-old adolescents who were part of nutrition and public health intervention as children (under 6 years old) n = 1165 adolescents Nutritional supplementation (protein-calorie supplementation) and public health programmes 3 years Yes

In exposed to intervention:

14 mm (p = 0.07) taller

Cardiovascular health 20% (p = 0.02) more favorable insulin resistance index, 3.3% (P = 0.008) more favorable arterial health
Nkhoma, O.W.W. et al., 2013 [30] Malawi Prospective cohort study

6–8-year-old children in Malawi

n = 226 children

School feeding program (increased micronutrient and caloric intake) 1 year No No significant effects on linear growth in comparison to control school Cognitive ability After 9-month exposure to supplement: decrease in errors made in one element of learning from 24.9 in control to 18.5 in intervention (p-interaction = 0.02)
Stein, A.D. et al., 2008 [36] Guatemala Prospective cohort study

Adults 25–42 exposed to supplementation trial from ages 0 to 7

n = 1448

Nutritional supplementation (protein supplementation beverage “atole”) 8 years Yes

- Stunting to < 20% (from baseline of 45%)

-2.4 cm (p < 0.005) increase in length of children at 3 years of age

Reading comprehension, cognitive functioning Exposure to supplement 0–12 mo.:6.39 [95%CI: 0.79–11.99] increase in reading comprehension score, 2.09 [95%CI: 0.79–3.99] increase in cognitive functioning score.
Argaw, A. et al., 2018 [27] Ethiopia 2 × 2 factorial randomized controlled trial

Mothers and their children ages 6–12 months in 3 districts of the Jimma zone in Southwest Ethiopia between November 2013 to February 2015

n = 360 mother-infant pairs

Nutritional supplementation (n-3 long-chain PUFA supplementation) 12 months No No significant effect of the supplementation was observed on linear growth. Child health No significant effect on morbidity or systemic inflammation.
van der Merwe, L.F. et al., 2013 [31] Gambia Randomized, double-blind control trial

Rural Gambian infants (3–9 months old)

n = 172

Nutritional supplementation (long-chain PUFA supplementation) 6 months No No significant effect of the supplementation was observed on linear growth. Cognitive development and morbidity in the infants No significant effects on cognitive development, intestinal function or morbidity were detected.
Yousafzai, A.K. et al., 2014 [42] Pakistan Cluster-randomised 2X2 factorial effectiveness trial

Children 0–24 months old

n = 1489

Nutritional supplementation (multiple micronutrient powders) 3 years Yes

Nutritional supplementation resulted in:

0.2 increase in HAZ score (p < 0.0001) at 6 mo. and 0.2 increase in HAZ score (p = 0.02) at 18 months.

Cognitive, language, motor and social-emotional development and child health

Nutritional supplementation resulted in:

3.4 higher cognition scores [95%CI: 1.1–5.7], 5.1 higher language scores [95%CI: 2.9–7.3], 2.9 higher motor score [95%CI: 0.5–5.3].

Samuel, A. et al., 2018 [28] Ethiopia Quasi-experimental matched-control study

Children 6–23 months old

N = 1172

Nutritional supplementation (complementary feeding program paired with low iron dose multiple micronutrient powders) 37 weeks Yes

Nutritional supplementation resulted in:

0.18 (SE: 0.05, p < 0.05) significant increase in HAZ score and an odds ratio (OR) for stunting of 0.49 [95% CI: 0.40–0.60] after 37 weeks of intervention (i.e. 51% reduced odds of stunting in the intervention group)

Child health No significant positive effects observed on child health.
Masuda, K. & Chitundu, M., 2019 [33] Zambia Two-arm randomized control trial

Children 6–18 months of age

N = 547

Nutritional supplementation (Micronutrient supplementation using spirulina platensis) 12 months No No significant effect on linear growth. Child health and motor development

Nutritional supplementation resulted in:

Reduction in the incidence of cough by 11% [95% CI : -0.23–0.00] and non-significant reductions in incidence of pneumonia (−0.17, [95% CI: −0.17,0.04]), severe fever (− 0.03, 95% CI = − 0.13, 0.06) and fever (− 0.09, [95% CI: − 0.19, 0.02])

Increase in probability of being able to walk alone by 15 months by 8% [95%CI : 0.02–0.14]