Table 1.
LAB species with available genome-scale metabolic models
| Species | Hetero-/homo-fermenter | Main applications and distinguishing characteristics | Genome size (Mb) | References |
|---|---|---|---|---|
| Lactobacillus reuteri | Hetero- | Produces Vitamin B12, 1,3-PDO, 3-HPA; used as probiotic and potential cell factory | 2.0 | [52], (This study) |
| Leuconostoc mesenteroides | Hetero- | Used in food fermentations (many non-dairy); malolactic fermentation; aroma production in foods | 2.0 | [29, 39] |
| Lactobacillus plantarum | Facultatively hetero- | Used in food fermentations, probiotics and potential cell factory | 3.3 | [61] |
| Lactobacillus casei | Facultatively hetero- | Used in food fermentations, probiotics and potential cell factory | 2.9 | [62] |
| Lactococcus lactis | Homo- | Used in dairy fermentations and potential cell factory | 2.4 | [38, 16] |
| Streptococcus thermophilus | Homo- | Used in dairy fermentations; fewer amino acid auxotrophies than other LAB, missing PPP genes | 1.9 | [42] |