Table 3.
Matrix effect and accuracy of the analytical method.
| aSpiked (ng mL−1) | bRE (%) | cRSD (%) | dME (%) | |
|---|---|---|---|---|
| 3 | 6.9 | 6.7 | 2.1 | 13.7 |
| 27.6 | 10.0 | 2.2 | 3.7 | |
| 165.6 | 4.6 | 0.8 | 6.4 | |
| 220.8 | 4.0 | 2.4 | — | |
| 4 | 24.75 | 6.1 | 8.5 | 8.6 |
| 99 | 1.5 | 2.9 | 1.1 | |
| 594 | 6.3 | 2.5 | 14.1 | |
| 792 | 4.1 | 3.8 | — | |
| 5 | 3.125 | 7.4 | 3.7 | 4.2 |
| 12.5 | 7.7 | 1.5 | 7.3 | |
| 75 | 4.7 | 1.2 | 10.6 | |
| 100 | 2.1 | 3.5 | — | |
| 6 | 6.5 | 9.8 | 3.9 | 15.8 |
| 26 | 1.5 | 3.8 | 8.8 | |
| 156 | 10.5 | 1.8 | 1.4 | |
| 208 | 1.9 | 4.2 | — |
aConcentration in the chromatography vial.
bR (%): recovery (mean of ten determinations).
cRSD (%): relative standard deviation (mean of ten determinations).
dME (%): matrix effect (mean of four determinations).