Fig 2. The relationship between odds of death and cumulative fluid balance.

Restricted cubic splines models. Confidence intervals (95%) are displayed in grey. Neutral fluid balance (0 mL) was used as reference (OR 1.0). A) Unadjusted odds ratios for 28-day mortality on the y-axis. On the x-axis cumulative fluid balance on day 7 in mL. B) Odds ratios for 28-day mortality on the y-axis, adjusted for severity of illness by APACHE II score. On the x-axis cumulative fluid balance on day 7 in mL.