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Variants in the rrs (16S rRNA) gene over the course of treatment. Patient 1: position 1174. Patient 2: position 1374, previously associated with amikacin resistance (see text). The numbering is relative to ATCC 19977 reference. Abbreviations: BAL, bronchoalveolar lavage; CW, chest wound; DSW, drain site swab; LN, lymph node; LT, lung tissue; PF, pleural fluid; S, sputum.
