Table 2.
Selected Sites, Healthcare Facilities, and Collaborating Institutions of the Severe Typhoid Fever in Africa Program
| Countrya | Study Site | Setting | Catchment population sizeb No. (Year) |
Healthcare facility | Healthcare facility type | Study periodc | Collaborating Institution | Site Laboratory |
|---|---|---|---|---|---|---|---|---|
| Burkina Faso | Ouagadougou | Urban | 2.57 million (2014) | a. Yalgado Hospital | Tertiary | Sep 2016-Jun 2019 | ISSP | Schiphra Hospital Laboratory |
| b. Charles de Gaulle Hospital | Pediatric Tertiary | Dec 2016-Jun 2019 | ||||||
| c. Kossodo Hospital | Secondary | May 2016-Dec 2020 | ||||||
| d. Polesgo Health Care Center | Primary | May 2016-Dec 2020 | ||||||
| Balé | Rural | 216,194 (2006) | Medically under-served area | ... | Apr 2017-Oct 2018 | |||
| Democratic Republic of Congo (DRC)d | Kisantu | Rural & Urban | 190,829 (2017) | a. Kisantu Hospital Saint-Luc | Tertiary | Sep 2017-Jan 2020 | NIBR | Saint Luc Kisantu Hospital Laboratory |
| b. Nkandu 1 Health Center | Primary | Jan 2018-Jan 2020 | ||||||
| c. Kavuaya Health Center | Primary | Jan 2018-Jan 2020 | ||||||
| n/a | n/a | n/a | Medically under-served area: n/a | n/a | n/a | |||
| Ethiopia | Wolayita Sodo | Semi-urban | 117,647 (2016) | a. Sodo Health Center | Primary | Jul 2017-Sep 2019 | AHRI | Sodo Teaching Hospital; Adama Regional Laboratory |
| b. Sodo Teaching Hospital | Secondary/ Tertiary | Jul 2017-Sep 2019 | ||||||
| c. Sodo Christian Hospital | Secondary/ Tertiary | Jul 2017-Sep 2019 | ||||||
| Adama Wenji | Semi-urban | 52,770 (2016) | a. Shewa Alem Tena Health Center | Primary | Aug 2017-Sep 2019 | |||
| b. Gefersa Health Center | Primary | Aug 2017-Sep 2019 | ||||||
| c. Kuriftu Health Center | Primary | Aug 2017-Sep 2019 | ||||||
| d. Adama Hospital | Secondary/ Tertiary | Aug 2017-Sep 2019 | ||||||
| n/a | n/a | n/a | Medically under-served area: n/a | n/a | n/a | |||
| Ghana | AAN & AAC |
Rural & Urban | 220,999 (2010) |
a. Agogo Presbyterian Hospital | Secondary | May 2016-May 2019 | KCCR; KNUST |
KCCR; KNUST |
| Kumasi Metropolis | Urban |
1.73 million (2010) |
a. Komfo Anokye Teaching Hospital |
Tertiary |
May 2016-May 2019 | |||
|
Tontokrom Keniago |
Rural Rural |
19,382 (2010) 15,808 (2010) |
Medically under-served area Medically under-served area |
... ... |
July 2016-Dec 2017 July 2016-Dec 2017 |
|||
| Madagascar | Antananarivo Renivohitra | Urban | 1.37 million (2015) | a. Centre Hospitalier Universitaire d’Antananarivo- Hopital Joseph Ravoahangy Andrianavalona (HJRA) |
Tertiary | May 2016-July 2019 | UOA | UOA |
| b. Centre Hospitalier Universitaire Joseph Raseta Befelatanana | Secondary/ Tertiary | June 2016-July 2019 | ||||||
| c. Centre Hospitalier Universitaire Mere Enfant Tsaralalana | Pediatric Secondary/ Tertiary | June 2016-July 2019 | ||||||
| Imerintsiatosika | Rural | 48,524 (2018) | a. Imerintsiatosika Centre de Santé de Base II (CSBII) | Primary | Feb 2016-July 2019 | |||
| Belobaka (in Mahajanga II) | Coastal | 9,238 (2019) | a. Belobaka Centre de Santé de Base II (CSBII) | Primary | June 2018-July 2019 | |||
| Andina commune Ilaka commune Tsarasaotra commune Antoetra commune |
Rural Rural Rural Rural |
24,425 (2015) 18,230 (2015) 23,290 (2015) 15,051 (2014) |
Medically under-served area Medically under-served area Medically under-served area Medically under-served area |
... ... ... ... |
Mar 2016-July 2019 Mar 2016-July 2019 Mar 2016-July 2019 Mar 2016-July 2019 |
|||
| Nigeria | Metropolitan Ibadan |
Urban | 1.34 million (2011) | a. University College Hospital | Tertiary | Feb 2017-July 2019 | UOI College of Medicine; University College Hospital |
University College Hospital, Department of Medical Microbiology and Parasitology |
| b. Our Lady of Apostles Catholic Hospital Oluyoro | Secondary | April 2017-July 2019 | ||||||
| c. Adeoyo Maternity Teaching Hospital | Secondary | May 2017-July 2019 | ||||||
| d. Kola Daisi Foundation Community Health Centre | Primary | April 2017-July 2019 | ||||||
| Ibarapa North | Semi-urban | 121,860 (2011) | Medically under-served area | ... | May 2018-July 2019 |
Abbreviations: DRC, Democratic Republic of Congo; n/a, not available; AAN, Asante Akim North; AAC, Asante Akim Central; ISSP, Institut Superieur des Sciences de la Population; NIBR, National Institute of Biomedical Research; AHRI, Armauer Hansen Research Institute; KCCR, Kumasi Center for Collaborative Research; KNUST, Kwame Nkrumah University of Science and Technology; UOA, University of Antananarivo; UOI, University of Ibadan
aEthical approval: International Vaccine Institute Institutional Review Board (IRB No. 2015-006); Institute of Tropical Medicine Antwerp Institutional Review Board, Belgium; Universiteit Antwerpen, Comite voor Medische Ethiek, Belgium; Ministère de la Santé du Burkina Faso, Comité d’Ethique pour la Recherche en Santé, Burkina Faso; Comité d’Ethique de l’Ecole de Santé Publique de l’Université de Kinshasa, Democratic Republic of Congo (No ESP/CE/011/2017); National Research Ethics Review Committee (NRERC), Ministry of Science and Technology, Federal Democratic Republic of Ethiopia; AHRI/All African Leprosy, Tuberculosis and Rehabilitation Training Center (ALERT) Ethics Review Committee (AAERC), Ethiopia; National Research Ethics Review Committee (NRERC), Ethiopia; Kwame Nkrumah University of Science and Technology, School of Medical Sciences/Komfo Anokye Teaching Hospital, Committee on Human Research, Publication and Ethics, Ghana; Ministère de la Santé du Repoblikan’l Madagaskar, Comité d’Ethique, Madagascar;University of Ibadan/University College Hospital Ethics Committee (No. UI/EC/16/0369), Ibadan, Nigeria; Ethics Committee, Our Lady of Apostles Catholic Hospital Oluyoro (OLA) (No. OCH/EC/17/05), Ibadan, Nigeria; Oyo State Ethics Review Committee (AD13/479/665A), Nigeria.
bSource of population data: see Figure 1. Population data of the medically under-served areas in Madagascar are from the respective commune census.
cStudy period for the surveillance activities including the enrolment of eligible participants and follow-ups.
dThe study duration in the DRC and Nigeria may be extended until July 2020 for additional one year surveillance activities.