Table 4.
Case Definitions
| Case Type | Definition |
|---|---|
| Confirmed TF case | Positive blood culture for Salmonella Typhi |
| Mild TF case | Blood culture–confirmed TF without any complication of TF listed in Table 6 |
| Severe TF casea | Blood culture confirmed TF with any one complication(s) of TF listed in Table 6 |
| Special caseb | Pathognomonic gastrointestinal perforations (ie, clinically diagnosed TF gastrointestinal perforation), even in the absence of laboratory confirmation, in patients living in and outside the defined catchment area |
| Confirmed PF case | Patients with a positive blood culture for Salmonella Paratyphi serovars |
| Confirmed iNTS disease case | Patients with a positive blood culture for any nontyphoidal Salmonella serovar |
| Relapse | Blood culture–confirmed case who becomes ill with a subsequent episode of TF/PF/iNTS disease within 90 days of the prime infection. (A relapse should be a discernably similar or identical infecting strain, for which further genomic analyses will be performed.) |
| Reinfection | Blood culture–confirmed case who becomes ill with a subsequent episode of TF/PF/iNTS disease on or after a 90-day period after documentation of a previous blood culture–confirmed TF/PF/iNTS disease. (A reinfection should be a discernably different infecting strain, for which further genomic analyses will be performed.) |
| S. Typhi/S. Paratyphi/NTS carrier | An individual shedding S. Typhi or S. Paratyphi or NTS in stool after symptom resolution. |