Table 1.
LYAR-associating proteins involved or expected to be involved in transcription
| Entry name | Protein name | Gene symbol | Gene ID | Note |
|---|---|---|---|---|
| Transcription-FACT complex | ||||
| SP16H_HUMAN | FACT complex subunit SPT16 | SUPT16H | 11198 | involved in rDNA transcription |
| SSRP1_HUMAN | FACT complex subunit SSRP1 | SSRP1 | 6749 | involved in rDNA transcription |
| Transcription-DSIF complex | ||||
| SPT5H_HUMAN | Transcription elongation factor SPT5 | SUPT5H | 6829 | involved in rDNA transcription |
| SPT4H_HUMAN | Transcription elongation factor SPT4 | SUPT4H1 | 6827 | involved in rDNA transcription |
| Transcription-PAF1 complex | ||||
| RTF1_HUMAN | RNA polymerase-associated protein RTF1 homolog | RTF1 | 23168 | involved in rDNA transcription |
| CTR9_HUMAN | RNA polymerase-associated protein CTR9 homolog | CTR9 | 9646 | involved in rDNA transcription |
| LEO1_HUMAN | RNA polymerase-associated protein LEO1 | LEO1 | 123169 | involved in rDNA transcription |
| WDR61_HUMAN | WD repeat-containing protein 61 | WDR61 | 80349 | involved in rDNA transcription |
| PAF1_HUMAN | RNA polymerase II-associated factor 1 homolog | PAF1 | 54623 | involved in rDNA transcription |
| Transcription-Super elongation complex (SEC) | ||||
| AFF4_HUMAN | AF4/FMR2 family member 4 | AFF4 | 27125 | |
| ENL_HUMAN | Protein ENL | MLLT1 | 4298 | |
| Kinase | ||||
| CD11B_HUMAN | Cyclin-dependent kinase 11B | CDK11B | 984 | |
| CSK22_HUMAN | Casein kinase II subunit alpha | CSNK2A2 | 1459 | |
| CSK2B_HUMAN | Casein kinase II subunit beta | CSNK2B | 1460 | |
| Topoisomerase & DNA damage | ||||
| TOP1_HUMAN | DNA topoisomerase 1 | TOP1 | 7150 | involved in rDNA transcription |
| DDB1_HUMAN | DNA damage-binding protein 1 | DDB1 | 1642 | |
| TOP2A_HUMAN | DNA topoisomerase 2-alpha | TOP2A | 7153 | involved in rDNA transcription |
| XRCC5_HUMAN | X-ray repair cross-complementing protein 5 | XRCC5 | 7520 | involved in rDNA transcription |
| Transcription-Other | ||||
| SAFB2_HUMAN | Scaffold attachment factor B2 | SAFB2 | 9667 | |
| SAFB1_HUMAN | Scaffold attachment factor B1 | SAFB | 6294 | |
| BRD4_HUMAN | Bromodomain-containing protein 4 | BRD4 | 23476 | |
| BRD2_HUMAN | Bromodomain-containing protein 2 | BRD2 | 6046 | |
| BRD3_HUMAN | Bromodomain-containing protein 3 | BRD3 | 8019 | |
| CN166_HUMAN | UPF0568 protein C14orf166 | C14orf166 | 51637 | |
| PELP1_HUMAN | Proline-, glutamic acid- and leucine-rich protein 1 | PELP1 | 27043 | involved in rDNA transcription |
| MATR3_HUMAN | Matrin-3 | MATR3 | 9782 | |
| RBP56_HUMAN | TATA-binding protein-associated factor 2N | TAF15 | 8148 | |
| T2FA_HUMAN | General transcription factor IIF subunit 1 | GTF2F1 | 2962 | |
| BCLF1_HUMAN | Bcl-2-associated transcription factor 1 | BCLAF1 | 9774 | |
| YLPM1_HUMAN | YLP motif-containing protein 1 | YLPM1 | 56252 | |
| TCOF_HUMAN | Treacle protein | TCOF1 | 6949 | involved in rDNA transcription |
| IWS1_HUMAN | Protein IWS1 homolog | IWS1 | 55677 | |
| SPT6H_HUMAN | Transcription elongation factor SPT6 | SUPT6H | 6830 | |
| MTA1_HUMAN | Metastasis-associated protein MTA1 | MTA1 | 9112 | |
| SATB2_HUMAN | DNA-binding protein SATB2 | SATB2 | 23314 | |
| MAX_HUMAN | Protein max | MAX | 4149 | involved in rDNA transcription |
| SLTM_HUMAN | SAFB-like transcription modulator | SLTM | 79811 | |
| TCF20_HUMAN | Transcription factor 20 | TCF20 | 6942 | |
| ILF3_HUMAN | Interleukin enhancer-binding factor 3 | ILF3 | 3609 | |
| S30BP_HUMAN | SAP30-binding protein | SAP30BP | 29115 | |