Table 1.
Difference between high-risk human papilloma virus (HPV)-positive and -negative patients in demographic characteristics
| Patients without high-risk HPV infection | Patients with high-risk HPV infection | P-value | |
|---|---|---|---|
| Crohn’s disease | N = 81 | N = 13 | |
| Age, years | 34.56 ± 4.61 | 36.15 ± 7.25 | 0.427 |
| Disease duration, years | 4.26 ± 3.63 | 8.69 ± 9.17 | 0.14 |
| Family history, n (%) | 0 (0.0) | 0 (0.0) | – |
| Behavior, n (%) | 0.839 | ||
| B1 (non-stricturing, non-penetrating) | 45 (55.6) | 6 (46.2) | |
| B2 (structuring) | 13 (16.0) | 2 (15.4) | |
| B3 (penetrating) | 23 (28.4) | 5 (38.4) | |
| Location, n (%) | 0.505 | ||
| L1 (terminal ileum) | 12 (14.8) | 2 (15.4) | |
| L2 (colon) | 7 (8.6) | 0 (0.0) | |
| L3 (ileocolon) | 48 (59.3) | 10 (76.9) | |
| L4 (upper gastrointestinal tract) | 14 (17.3) | 1 (7.7) | |
| Smoking, n (%) | 8 (9.9) | 1 (7.7) | 1.000 |
| Extra-intestinal manifestation, n (%) | 15 (18.5) | 1 (7.7) | 0.571 |
| Perianal disease, n (%) | 36 (44.4) | 5 (38.5) | 0.686 |
| Ulcerative colitis | N = 26 | N = 4 | |
| Age, years | 39.24 ± 8.72 | 35.75 ± 6.02 | 0.450 |
| Disease duration, years | 4.01 ± 3.57 | 6.17 ± 3.09 | 0.266 |
| Family history, n (%) | 0 (0.0) | 0 (0.0) | – |
| Location, n (%) | 0.662 | ||
| E1 (ulcerative proctitis) | 4 (15.4) | 0 (0.0) | |
| E2 (left-sided) | 4 (15.4) | 1 (25.0) | |
| E3 (extensive) | 18 (69.2) | 3 (75.0) | |
| Smoking, n (%) | 0 (0.0) | 0 (0.0) | – |
| Extra-intestinal manifestation, n (%) | 1 (3.8) | 0 (0.0) | 1.000 |