Table 2.
Age, Pretreatment, Hospital Admission, and Extended-spectrum β-Lactamase (ESBL) Status of Patients With ESBL Gram-negative Bloodstream Infections
| All Countries Except Ghana | Ghana Only | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Phenotypic | Genotypic | Phenotypic | Genotypic | |||||||||
| ESBL Positive | ESBL Negative | P Value | ESBL Positive | ESBL Negative | P Value | ESBL Positive | ESBL Negative | P Value | ESBL Positive | ESBL Negative | P Value | |
| Age Group | n | n | n | n | n | n | n | n | ||||
| 0 to ≤1 yr | 3 | 29 | .246 | 1 | 31 | .667 | 24 | 76 | .001 | 27 | 73 | <.001 |
| >1 yr to ≤2 yrs | 1 | 10 | .560 | 1 | 10 | .457 | 0 | 27 | .968 | 0 | 27 | .970 |
| >2 yrs to ≤3 yrs | 0 | 8 | .977 | 0 | 8 | .979 | 4 | 17 | .728 | 1 | 20 | .229 |
| >3 yrs to ≤4 yrs | 0 | 2 | .988 | 0 | 2 | .989 | 0 | 4 | .988 | 0 | 4 | .989 |
| >4 yrs to ≤5 yrs | 0 | 4 | .984 | 0 | 4 | .985 | 0 | 3 | .989 | 0 | 3 | .990 |
| >5 yrs to ≤10 yrs | 2 | 12 | .134 | 1 | 13 | .620 | 4 | 9 | .161 | 2 | 11 | .889 |
| >10 yrs to ≤18 yrs | 0 | 6 | .980 | 0 | 6 | .981 | 4 | 11 | .274 | 4 | 11 | .159 |
| >18 yrs to ≤35 yrs | 1 | 22 | .829 | 2 | 21 | .303 | 1 | 20 | .167 | 1 | 20 | .2291 |
| >35 yrs to ≤50 yrs | 0 | 17 | .966 | 0 | 17 | .667 | 2 | 15 | .599 | 0 | 17 | .976 |
| >50 yrs | 0 | 16 | .967 | 1 | 15 | .457 | 4 | 38 | .200 | 2 | 40 | .076 |
| Total patients (%) | 7 (5.3%) | 126 (94.7%) | 6 (4.5%) | 127 (95.5%) | 43 (16.3%) | 220 (83.4%) | 37 (14.1%) | 226 (85.9%) | ||||
| Taken antimalarial prior to consultation | 1 | 21 | .869 | 1 | 21 | .993 | 4 | 24 | .755 | 2 | 26 | .277 |
| Taken antimicrobial prior to consultation | 2 | 18 | .317 | 1 | 19 | .909 | 1 | 22 | .137 | 2 | 21 | .444 |
| Admitted to hospital | 3 | 50 | .868 | 3 | 50 | .606 | 38 | 197 | .820 | 35 | 200 | .277 |
Abbreviation: ESBL, extended spectrum β-lactamase.