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IL-1β and PD98059 differentially affect nuclear translocation and accumulation of phospho-ERK1/2 in NESC (pixel quantification from immunofluorescence cytochemistry).
| ESC treatment | Phospho-ERK1/2 (nuclear pixels % relative to control) |
|---|---|
| Control | 100 ± 5% |
| IL-1β | 211 ± 7%* |
| PD98059 | 84 ± 4%* |
| IL-1β + PD98059 | 111 ± 4%** |
* P < 0.01 vs control.
** P < 0.05 vs PD98059
